How does it work?

IMPLANTATION
Mixing BoneAlbumin with a drop of blood results in an easily formable paste, which can be implanted into the bone cavity with a Volkmann spoon. It can be compressed or mixed with autogenous bone, if necessary.

STEM CELLS
The morphology and components of human bone form an ideal frame, while the local high albumin concentration supports the growth of stem cells and therefore the growth of the new tissue, as well.

RESTRUCTURING
The crystalline frame of BoneAlbumin fills the whole cavity during its slow degradation until the slowly formed bone tissue takes its place.

NEW BONE
A strong and load-bearing bone providing an ideal support for the implants is the result of the complete integration and restructuring of the graft.
Scientific results

ELECTRON MICROSCOPY
demonstrated that bone marrow stem cells adhere and proliferate on the surface of BoneAlbumin while cells were hardly detected on the surface of bovine bone or ceramics.

IN ANIMAL STUDIES
albumin coating accelerated graft integration and, more importantly, resulted in high- density bone with increased fracture resistance.

IN ORTHOPEDICS
BoneAlbumin has been used for filling large bone defects since 2010. Multiple authorized studies have demonstrated its safety and efficacy.

DOUBLE-BLIND
human oral surgeon studies evinced that BoneAlbumin results better integration into the human body comparing to BioOss when they were used for socket preservation.
Who are we?
OrthoSera is a regenerative medicine company harnessing the power of blood serum for human diseases. Our R&D is currently focused on bone grafting, osteoarthritis, wound healing, as well as dental and orthopedic indications. Blood serum has a high regenerative potential and based on this fact OrthoSera has already developed two technologies.
BoneAlbumin is essentially a serum albumin enhanced bone allograft that was shown to activate bone marrow stem cells leading to faster and better bone healing. This tissue product is already in commercial stage with two double-blind clinical studies proving its effectiveness in sports surgery and dentistry. Our next technology takes this concept even further, as we use a proprietary method to isolate a specific, growth-factor rich serum fraction (hyperacute serum or hypACTTM) that has shown superior effects in promoting cell proliferation in osteoarthritic bone, cartilage, and mesenchymal stem cells among others.
Hyperacute serum is also patent-covered and can be applied at the bedside with our CE-marked medical device, hypACT inject.
Learn About Our Leading Technologies
OrthoSera received an innovation prize
OrthoSera Kft received the TOP10 most interesting hungarian innovation 2018-2019 prize for the BoneAlbumin product!
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Read morePerspectives in Perio-Implantology and Comprehensive Dentistry
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Perfect solution
The human bone substitute is recognized as “more identical”, and the human body gives it a warmer welcome than the products from another species..